Phytochemical Screening and Antidengue Activity of Jatropha Multifida Extract against DENV-2

Cases of dengue infection are still high in various parts the world and no antiviral has been found to treat infection. Jatropha multifida is one herbs used by community infection, but pre-clinical clinical scientific evidence not carried out. Phytochemical screening ethanol extract leaves was out using thin layer chromatography. Cytotoxic assay performed on Vero cells MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide). The cytotoxic concentration 50 (CC50) determined probit analysis. Anti-dengue test virus serotype 2 (DENV-2) RNA (ribonucleic acid) copy number quantified quantitative polymerase chain reactions ((qPCR). results showed that contains flavonoid terpenoid compounds. CC50 be 651.8 µg/mL. treated group lower than control difference significant. anti-dengue activity against DENV-2.